解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Changes of the complement components in the sera of 13 children with treated coeliac disease were studied after gluten challenge. The levels of C 1 and C3-activator (factor B) were significantly decreased at 4 h after the challenge, as were the levels of total complement (CH 50) and the components C 1, C 4 and C 1-ina...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF01846034
更新日期:1980-08-01 00:00:00
abstract::Children with symptomatic hypoglycemia and asymptomatic hypoglycemia-prone children were shown to differ in the degree of ketosis after a 20 h fast. In the latter children the close negative correlation between ketone body levels and glucose levels yielded a regression line against which the former children's data cou...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00442403
更新日期:1980-06-01 00:00:00
abstract::The light- and electron-microscopic structure of articular and costal cartilage in a case of achondrogenesis type I has been described. The most characteristic ultrastructural change in the chondrocytes was conspicuous dilatation of the rough endoplasmatic reticulum (RER) which contained amorphous electronopaque mater...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00442406
更新日期:1980-06-01 00:00:00
abstract::Following ion-exchange chromatography and subsequent thin-layer chromatography, 3 peculiar oligosaccharide excretion patterns were distinguished in 3 patients with beta-galactosidase deficiency. Each patient differed clinically and it is proposed that this method may be of use in characterizing various forms of beta-g...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00496087
更新日期:1980-05-01 00:00:00
abstract::An apparently hitherto undescribed, severe skeletal syndrome is reported in 3 siblings (2 boys, 1 girl) in a family of Turkish-Arabian descent. Major manifestations include: hypoplasia of the pelvis, congenital dislocation of the hip, severe bowing of femora, aplasia or hypoplasia of fibulae, absence or coalescence of...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00441580
更新日期:1980-03-01 00:00:00
abstract::Serum creatinine, uric acid, and hypoxanthine and xanthine concentrations were determined in 17 mother-infant pairs at the time of delivery. Creatinine and uric acid levels were nearly similar, but hypoxanthine and xanthine were more than twice as high in the blood of the infants than in the blood of their mothers. In...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00441585
更新日期:1980-03-01 00:00:00
abstract::Following a description of the genetic aspects of the human histocompatibility antigens system HLA and its principle typing methods, this paper reviews the relationship between HLA antigens, transplantation immunology and certain diseases. In particular, the role of the lymphocyte-defined antigens of the HLA-D system ...
journal_title:European journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/BF00441576
更新日期:1980-03-01 00:00:00
abstract::We report a 13 year-old girl with manifestations strikingly reminiscent of the tricho-rhino-phalangeal (TRP) II or Langer-Giedion syndrome. A terminal deletion of 8q must be assumed to be the cause of her condition till proven otherwise. A similar chromosome abnormality should be searched for (blindly) in other cases ...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00441586
更新日期:1980-03-01 00:00:00
abstract::Forty newborns with severe shock and disseminated intravascular coagulation were randomized for treatment with heparin or placebo. Mortality was equal in both groups. The heparin group required significantly shorter periods of artificial ventilation. The coagulation system improved faster, and the coagulation pattern ...
journal_title:European journal of pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF00444754
更新日期:1980-01-01 00:00:00
abstract::The study material consisted of 251 newborn light-treated infants with rhesus haemolytic disease (RHD) caused by anti-D. 139 infants were treated with ordinary phototherapy (white single light) and 112 infants with intensive phototherapy (blue double light). An evaluation was made as to wheter the indications for earl...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00444752
更新日期:1980-01-01 00:00:00
abstract::Small for gestational age (SGA) infants are known to develop relatively mild transient hyperbilirubinaemia, especially in comparison with premature infants. This may be interpreted as an index of accelerated maturation of particular vital functions. In the present study 12 SGA infants, 12 appropriate for gestational a...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00442433
更新日期:1979-11-01 00:00:00
abstract::We describe here an infant with a large, solitary, fluid-filled lung cyst and hyperinflation of adjacent lung tissue in the same lobe. The combination of a fluid-filled cyst and ectatic emphysema in the same lobe suggests bronchial collapse and airway obstruction as a contributory mechanism for this unusual roentgenog...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00447379
更新日期:1979-10-01 00:00:00
abstract::We report a female newborn with focal dermal hypoplasia (Goltz-Gorlin Syndrome) and marked asymmetric malformations on the right side of the body. Diaphragmatic hernia on the same side, which has not been reported in this syndrome, led to perinatal complications. ...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00538945
更新日期:1979-06-28 00:00:00
abstract::A benign cystic nephroblastoma in a 6-month-old boy is presented. Erroneous interpretation as malignant nephroblastoma led to unnecessarily aggressive therapy. There is no evidence of recurrence or metastatic disease 12 years after the initial resection. As shown in our case and in the others previously reported in th...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00447474
更新日期:1979-05-18 00:00:00
abstract::To nine cystic fibrosis patients with chronic bronchopulmonary infection of severely damaged lungs invaded by Pseudomonas aeruginosa, eleven courses of prolonged tobramycin treatment (5 mg/kg/day) for four to 16 weeks were administered. Pulmonary symptoms improved and a better quality of life was achieved in all but o...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00441362
更新日期:1979-04-03 00:00:00
abstract::A new method for the detection of hyperammonemia, using a kit based on the principle of microdiffusion of ammonia, is described. The method requires only one drop of blood and takes only 15 min to complete. Experiments for recovery and reproducibility were satisfactory, and good correlation was obtained when compared ...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00442347
更新日期:1979-02-08 00:00:00
abstract::Twenty patients with rheumatoid arthritis or Still's disease associated with growth failure were treated with human growth hormone, 7.5 to 17 U/m2 body surface per week. Five patients did not respond with better growth. In the remainder the mean growth rate increased from 1.9 cm/year (range: 0 to 3.3) to 6.2 cm/year (...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00441894
更新日期:1979-01-18 00:00:00
abstract::To find out whether cytomegalovirus (CMV) infection during the first months of life influences child development, developmental assessment at the age of 2 years was performed on 116 Finnish children chosen at random in a maternity hospital and followed from birth for the occurrence of CMV infection. Two of the childre...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00496851
更新日期:1979-01-01 00:00:00
abstract::This paper describes the design of a study to follow the development of boys and girls in secondary schools from the age of 12 through 17 on an annual basis, in order to acquire more information concerning the growth and development of teenagers. In this study, both physical and psychological characteristics are measu...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00442158
更新日期:1978-10-12 00:00:00
abstract::Two siblings with increased levels of serum phenylalanine were detected by newborn screening. The older sibling deteriorated neurologically and mentally, despite early dietary control, and died at the age of 6 1/2 years. In the younger sibling phenylalanine hydroxylase activity in liver tissue was normal. Further inve...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00442368
更新日期:1978-09-08 00:00:00
abstract::The topography and morphology of the lacrimal ducts in newborn infants was demonstrated by means of post mortem dacryocystograms and microphotograms of histologic slides. Because of bends in the course of the lower tear duct, a percentage of probings will fail to effect satisfactory perforation of the Hasner membrane....
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00442367
更新日期:1978-09-08 00:00:00
abstract::Clinically visible corneal opacities were observed in a patient with an extremely severe form of mucopolysaccharidosis II. In a second patient with an unusually mild form of mucopolysaccharidosis II, discrete corneal opacities were detected by slit-lamp examination. Thus clear corneae can no longer be regarded as a ha...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00441369
更新日期:1978-08-17 00:00:00
abstract::A 22 years old female with the late-onset of argininosuccinic aciduria was successfully treated for 5 months with a mixture of essential amino acids and their keto-analogues. There was a marked change in plasma ammonia, plasma amino acids and argininosuccinic acid excretion. A long term anabolic response was reflected...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00445607
更新日期:1978-07-19 00:00:00
abstract::Factor VIII procoagulant activity and factor VIII related antigen were examined in 20 full-term and preterm newborn infants during the first days of life. The control group involved 15 adults volunteers. Factor VIII activity was estimated by a one-stage test and factor VIII related antigen was determined by immunelect...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00445613
更新日期:1978-07-19 00:00:00
abstract::Cortisol and growth hormone (GH) secretion (spontaneous variations at night and the release induced by insulin hypoglycaemia) were investigated in 69 children and adolescents. Statistical analysis of approximately 600 pairs of cortisol and GH values in this study demonstrated that physiological fluctuations of cortiso...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00496996
更新日期:1978-06-20 00:00:00
abstract::Vascularization of the arms has been studied by impedance plethysmography (rheography) in eight children with Poland syndrome, a common malformation characterized by unilateral hand anomaly and ipsilateral aplasia of the inferior head of the pectoralis major muscle. A marked decrease of the velocity of the systolic in...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00496922
更新日期:1978-05-22 00:00:00
abstract::The first Scandinavian cases of Zellweger syndrome (ZS) are described. A brother and sister, children of first cousins, had the typical clinical symptoms and pathological findings. Extensive metabolic studies in the boy were negative. Pipecolic acid in the urine was not elevated. Both children died at 14 weeks of age....
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00493539
更新日期:1978-04-20 00:00:00
abstract::Serum lysozyme activity was measured in samples from children with acute leukemia, malignant tumours, and in normal children. All children with acute lymphatic leukemia (ALL) had significantly reduced levels of lysozyme at diagnosis, and none of the children fell within the normal range. Children with ALL in complete ...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00493542
更新日期:1978-04-20 00:00:00
abstract::Seven male Japanese children with chronic granulomatous disease were given sulfamethoxazole-trimethoprim (SMX-TMP) for recurrent pyogenic infections, most of which had proved difficult to control with other antibiotics. With continous treatment the children remained free of infections severe enough to necessitate hosp...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00493540
更新日期:1978-04-20 00:00:00
abstract::One hundred and twenty two cases of severe hyaline membrane disease are reported. 68 of them survived (57%). Adverse clinical, radiological and laboratory factors, and their effects on the early mortality rate, are analysed with particular reference to the referring centers, delay in admission, transport and the criti...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00442059
更新日期:1978-03-13 00:00:00
abstract::An infant girl three weeks of age with the leading symptom of skin haemorrhages is presented. On further investigation, the signs of severe hepatic damage with hypofibrinogenaemia and prothrombin complex impairment, and renal tubular dysfunction were disclosed. All these pathological symptoms, which were reversed on f...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00465567
更新日期:1977-12-30 00:00:00
abstract::The clinical and biochemical response to 25-hydroxycholecalciferol (25-HCC) and vitamin D3, 150 microgram/day for 20 days has been compared in infants aged 3--18 months with nutritional rickets. The infants were allocated at random to Group I (11 infants) treated with 25HCC and Group II (9 infants) treated with vitami...
journal_title:European journal of pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF00465565
更新日期:1977-12-30 00:00:00
abstract::In fourteen infants, aged 9--60 days, with generalized oedema seen during a one year period the common denominator was the administration of dipyrone one to two days prior to the development of oedema. None of the other causes of oedema in early life could be incriminated in any of these babies. Pediatricians should b...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00477053
更新日期:1977-11-04 00:00:00
abstract::The pre- and postnatal clinical, cytogenetic and embryological findings in a family suffering from trisomy 9p and spinal muscular atrophy are presented. The clinical picture of the "trisomy 9p" -syndrome is delineated. Concurrence of autosomal aberration and spinal muscular atrophy, probably of the Werdnig-Hoffmann ty...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00443119
更新日期:1977-08-23 00:00:00
abstract::The correlation between the appearance of functionally-atypical factor VII and perinatal complications was investigated in 66 newborn infants. The presence of an abnormal clotting factor was assumed if the ratio between clotting activity and antigen-related factor VII material exceeded the normal range for adult plasm...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00493570
更新日期:1977-08-12 00:00:00
abstract::Blood volume was estimated using 51chromium labelled red cells and 125iodinated human serum albumin in 5 children with sepsis, in 6 burned children and 7 children with acute lymphoblastic leukaemia. Studies of the equilibration pattern demonstrated that the mixing time of labelled red cells was prolonged to 40 minutes...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00489987
更新日期:1977-06-01 00:00:00
abstract::A patient with a cerebro-hepato-renal syndrome was investigated. The visceral manifestations were those of the Zellweger syndrome (ZS); however, the child exhibited muscular hypertonia and survived into the 2nd year of life. Ultramicroscopically, hepatocytes were lacking peroxisomes, but, contrary to findings in one p...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00441934
更新日期:1977-03-18 00:00:00
abstract::In 23 subjects of different ages with Down's syndrome a number of parameters of non-specific defense of humoral and cellular immunity were investigated. While in all age groups complement factors C3, C4 and C5 as well as phagocytosis and NBT indices were in the normal range, a dysgammaglobulinaemia increasing with age...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00477543
更新日期:1977-01-26 00:00:00
abstract::Within a 2-year period, from March 1974 until May 1976 10 patients with anorexia nervosa were seen at the children's university hospitals of München (2 patients) and Giessen (8 patients). The patients were 10-16 years old, with one exception all girls, and had the typical cachexia, hypothermia, bradycardia, gray, hair...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00452416
更新日期:1976-12-09 00:00:00
abstract::We report mother and son with the ulnar-mammary syndrome type Pallister: both had postaxial polydactyly in one upper limb and absence or hypoplasia of the axillary apocrine glands bilaterally. The mother had total lack of the mammary gland tissue and absence of one kidney. Her son also had unilateral oligodactyly, an ...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00444644
更新日期:1976-11-03 00:00:00